Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.44 |
| ▸ | RXRA | P19793 | 10/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRG | P48443 | 2/20 | 0.43 |
| ▸ | RARG | P13631 | 4/20 | 0.42 |
| ▸ | RARB | P10826 | 4/20 | 0.42 |
| ▸ | RARA | P10276 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7025024 | 0.93 | RXRA (0.46) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL6870756 | 0.82 | PTPN11 (0.52) | PTPN11RXRARXRBRXRGRARG | |
| SCHEMBL6875753 | 0.81 | RXRA (0.44) | PTPN11RXRARXRBRXRGRARG | |
| SCHEMBL6877473 | 0.80 | RXRA (0.43) | PTPN11RXRARXRBRXRGRARG | |
| SCHEMBL6877472 | 0.80 | PTPN11 (0.48) | PTPN11RXRARXRBRXRGRARG | |
| SCHEMBL6870757 | 0.80 | RXRA (0.48) | PTPN11RXRARXRBRXRGRARG | |
| SCHEMBL6879665 | 0.75 | RXRA (0.49) | PTPN11RXRARXRBRXRGRARG | |
| SCHEMBL6878500 | 0.73 | RXRA (0.46) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL6874354 | 0.73 | RXRA (0.48) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL6876044 | 0.73 | RXRA (0.45) | RXRARXRBRXRGRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832081-B1 | BICYCLIC-AROMATIC COMPOUNDS | GALDERMA RECH DERMATOLOGIQUE (FR) | 2003-01-29 | — | — | EP | disclosed |
| EP-0832081-A1 | BICYCLIC-AROMATIC COMPOUNDS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997033881-A1 | BICYCLIC-AROMATIC COMPOUNDS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1997-09-18 | — | — | WO | disclosed |