SCHEMBL7027969

SCHEMBL7027969

CC(=O)OCC1=CCC(C)CC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
CCR2 P41597 13/20 0.35
NLRP3 Q96P20 2/20 0.33
CYP3A4 P08684 1/20 0.33
GSTP1 P09211 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24329178 0.67 ALDH1A1 (0.38) ALDH1A1CYP3A4GSTP1
SCHEMBL22015751 0.66 ALDH1A1 (0.37) ALDH1A1CYP3A4GSTP1
SCHEMBL22826554 0.65
SCHEMBL21963892 0.65 ALDH1A1 (0.36) ALDH1A1GSTP1
SCHEMBL23163121 0.65 ALDH1A1 (0.36) ALDH1A1GSTP1
SCHEMBL23544215 0.63 ALDH1A1 (0.38) ALDH1A1NLRP3CYP3A4GSTP1
SCHEMBL14855693 0.63
SCHEMBL12032197 0.62 TDP1 (0.49)
SCHEMBL15798092 0.62 TDP1 (0.49)
SCHEMBL15798094 0.62 TDP1 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0955290-B1 Unsaturated ketones and their use in perfumery FIRMENICH & CIE (CH) 2003-03-19 EP disclosed
US-6177400-B1 IMPROVING OR MODIFYING THE ODOR OF A PERFUME BY ADDING 4,6,6-TRIMETHYL-1,(3)-CYCLOHEX(ADI)ENE 1-SUBSTITUTED WITH ESTERS, ETHERS OR KETONES, SUCH AS (E)-1-(4,6,6-TRIMETHYL-1,3-CYCLOHEXADIEN-1-YL)-2-BUTEN-1-ONE FIRMENICH SA (CH) 2001-01-23 US disclosed
EP-0955290-A1 Unsaturated ketones and their use in perfumery FIRMENICH SA (CH) 1999-11-10 EP disclosed