Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | P4HB | P07237 | 1/20 | 0.49 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.49 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31513646 | 1.00 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL16327524 | 1.00 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL230378 | 1.00 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL2786496 | 1.00 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL230379 | 1.00 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL13435245 | 1.00 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL1527155 | 1.00 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL7028056 | 1.00 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL13461633 | 1.00 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 | |
| SCHEMBL31180770 | 1.00 | TSHR (0.54) | TSHRLMNAP4HBPDIA4PDIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6538117-B1 | Linear sequence of three or more glycosyl units linked to one another by glycosidic linkages; database of reactivity values for glycosyl donors | THE SCRIPPS RESEARCH INSTITUTE | 2003-03-25 | — | — | US | disclosed |
| US-5637569-A | FORMING ANTIBODIES; INDUCE IMMUNOLOGY RESPONSE | SYMBICOM AKTIEBOLAG (SE) | 1997-06-10 | — | — | US | disclosed |
| WO-1993010134-A1 | GANGLIOSIDE ANALOGS | SYMBICOM AKTIEBOLAG (SE) | 1993-05-27 | — | — | WO | disclosed |