SCHEMBL230378

SCHEMBL230378

CC(=O)OC[C@H]1OC(OC(C)=O)[C@H](N2C(=O)c3ccccc3C2=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.54
▸ LMNA P02545 3/20 0.53
▸ P4HB P07237 1/20 0.49
▸ PDIA4 P13667 1/20 0.49
▸ PDIA3 P30101 1/20 0.49
▸ KMT2A Q03164 1/20 0.48
▸ PRKCA P17252 1/20 0.48
▸ AKT1 P31749 1/20 0.48
▸ PTK2 Q05397 1/20 0.48
▸ THRB P10828 2/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ HIF1A Q16665 1/20 0.47
▸ PTPN1 P18031 1/20 0.47
▸ CYP2D6 P10635 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ PAX8 Q06710 1/20 0.46
▸ TGM2 P21980 1/20 0.45
▸ CA12 O43570 2/20 0.45
▸ CA1 P00915 2/20 0.45
▸ CA2 P00918 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31513646 1.00 TSHR (0.54) TSHRLMNAP4HBPDIA4PDIA3
SCHEMBL16327524 1.00 TSHR (0.54) TSHRLMNAP4HBPDIA4PDIA3
SCHEMBL2786496 1.00 TSHR (0.54) TSHRLMNAP4HBPDIA4PDIA3
SCHEMBL7028051 1.00 TSHR (0.54) TSHRLMNAP4HBPDIA4PDIA3
SCHEMBL230379 1.00 TSHR (0.54) TSHRLMNAP4HBPDIA4PDIA3
SCHEMBL13435245 1.00 TSHR (0.54) TSHRLMNAP4HBPDIA4PDIA3
SCHEMBL1527155 1.00 TSHR (0.54) TSHRLMNAP4HBPDIA4PDIA3
SCHEMBL7028056 1.00 TSHR (0.54) TSHRLMNAP4HBPDIA4PDIA3
SCHEMBL13461633 1.00 TSHR (0.54) TSHRLMNAP4HBPDIA4PDIA3
SCHEMBL31180770 1.00 TSHR (0.54) TSHRLMNAP4HBPDIA4PDIA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167148-A1 MODULAR SYNTHESIS OF AMINOGLYCOSIDES REVAGENIX, INC. 2023-06-01 — — US disclosed
US-20220411456-A1 MODULAR SYNTHESIS OF AMINOGLYCOSIDES REVAGENIX, INC. (US) 2022-12-29 — — US disclosed
US-11021547-B2 Method of synthesising 6-deoxy-6-amino-β-D-glucopyranoside-containing polymers and their precursors UNIVERSITY OF CAPE TOWN (ZA) 2021-06-01 — — US disclosed
US-10806746-B2 Di- and tri-cationic glycosylated antitumor ether lipids, L-gucosylated gaels and rhamnose-linked gaels as cytotoxic agents against epithelial cancer cells and cancer stem cells THE UNIV OF MANITOBA (CA) 2020-10-20 — — US disclosed
US-20200325250-A1 METHOD OF SYNTHESISING 6-DEOXY-6-AMINO-ß-D-GLUCOPYRANOSIDE-CONTAINING POLYMERS AND THEIR PRECURSORS UNIVERSITY OF CAPE TOWN (ZA) 2020-10-15 — — US disclosed
WO-2019194858-A1 MODULAR SYNTHESIS OF AMINOGLYCOSIDES ACHAOGEN, INC. (US) 2019-10-10 — — WO disclosed
WO-2019046126-A1 AMINOGLYCOSIDES AND USES THEREOF ACHAOGEN, INC. (US) 2019-03-07 — — WO disclosed
US-20160007600-A1 SYNTHETIC LIPOCHITOOLIGOSACCHARIDE ANALOGS FOR ENHANCING PLANT PERFORMANCE DU PONT (US) 2016-01-14 — — US disclosed
US-20150305333-A1 USE OF GLUCOSAMINE AMIDES AS PLANT GROWTH AND YIELD ENHANCERS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2015-10-29 — — US disclosed
WO-2015130893-A1 SYNTHETIC OLIGOGLUCOSAMINES FOR IMPROVEMENT OF PLANT GROWTH AND YIELD E. I. DU PONT DE NEMOURS AND COMPANY (US) 2015-09-03 — — WO disclosed
US-20090176970-A1 Preparation of Thiosugars and Their Use GLYCOFORM LIMITED (GB) 2009-07-09 — — US disclosed
US-7485718-B2 Chemical synthesis of low molecular weight polyglucosamines and polygalactosamines E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-02-03 — — US disclosed
US-20080033155-A1 PROCESSES FOR THE PRODUCTION OF AMINOALKYL GLUCOSAMINIDE PHOSPHATE AND DISACCHARIDE IMMUNOEFFECTORS, AND INTERMEDIATES THEREFOR CORIXA CORPORATION (US) 2008-02-07 — — US disclosed
US-7288640-B2 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor CORIXA CORPORATION (US) 2007-10-30 — — US disclosed
US-20070238872-A1 Processes for chemical synthesis of lipochitooligosaccharides E. I. DU PONT DE NEMOURS AND COMPANY 2007-10-11 — — US disclosed
WO-2007001282-A2 LOW MOLECULAR WEIGHT POLYGLUCOSAMINES AND POLYGALACTOSAMINES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-01-04 — — WO disclosed
US-20060286149-A1 Low molecular weight polyglucosamines and polygalactosamines E. I. DU PONT DE NEMOURS AND COMPANY 2006-12-21 — — US disclosed
US-20060287515-A1 Chemical synthesis of low molecular weight polyglucosamines and polygalactosamines E. I. DU PONT DE NEMOURS AND COMPANY 2006-12-21 — — US disclosed
WO-2006012425-A2 PROCESSES FOR THE PRODUCTION OF AMINOALKYL GLUCOSAMINIDE PHOSPHATE AND DISACCHARIDE IMMUNOEFFECTORS, AND INTERMEDIATES THEREFOR CORIXA CORPORATION (US) 2006-02-02 — — WO disclosed
US-20050107600-A1 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor CORIXA CORPORATION, A CORPORATION OF THE STATE OF DELAWARE (US) 2005-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160007600-A1 SYNTHETIC LIPOCHITOOLIGOSACCHARIDE ANALOGS FOR ENHANCING PLANT PERFORMANCE LIPC, DDOST, MAGT1 TSHR 2195/4885LMNA 3779/4885P4HB 4309/4885
US-20060286149-A1 Low molecular weight polyglucosamines and polygalactosamines ALG1, B3GNT2, OGT TSHR 3958/4885LMNA 2338/4885P4HB 4567/4885
US-20150305333-A1 USE OF GLUCOSAMINE AMIDES AS PLANT GROWTH AND YIELD ENHANCERS NANS, UGCG, B3GNT2 TSHR 2212/4885LMNA 1948/4885P4HB 2563/4885
US-20050107600-A1 Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor DDOST, AGL, GALE TSHR 3883/4885LMNA 4696/4885P4HB 466/4885
US-20090176970-A1 Preparation of Thiosugars and Their Use TST, TREH, FUT6 TSHR 1206/4885LMNA 3594/4885P4HB 97/4885
US-10806746-B2 Di- and tri-cationic glycosylated antitumor ether lipids, L-gucosylated gaels and rhamnose-linked gaels as cytotoxic agents against epithelial cancer cells and cancer stem cells PNLIP, UGCG, LIPC TSHR 2142/4885LMNA 3420/4885P4HB 3235/4885
US-20230167148-A1 MODULAR SYNTHESIS OF AMINOGLYCOSIDES MRPL21, COASY, AARS1 TSHR 3997/4885LMNA 2679/4885P4HB 702/4885
US-20220411456-A1 MODULAR SYNTHESIS OF AMINOGLYCOSIDES MRPL21, COASY, AARS1 TSHR 3997/4885LMNA 2679/4885P4HB 702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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