Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.50 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10661484 | 1.00 | TSHR (0.61) | TSHRTHRATHRBSMPD1APP | |
| SCHEMBL10660855 | 0.98 | TSHR (0.58) | TSHRTHRATHRBSMPD1APP | |
| SCHEMBL7022072 | 0.93 | FAAH (0.56) | TSHRAPPFAAHMTNR1AMTNR1B | |
| SCHEMBL12589667 | 0.93 | TSHR (0.54) | TSHRTHRATHRBSMPD1APP | |
| SCHEMBL9911816 | 0.88 | APP (0.55) | TSHRAPPFAAHMTNR1AMTNR1B | |
| SCHEMBL28203174 | 0.87 | TSHR (0.62) | TSHRTHRATHRBSMPD1MTNR1A | |
| SCHEMBL7455570 | 0.86 | APP (0.60) | TSHRAPPFAAHMTNR1AMTNR1B | |
| SCHEMBL10663047 | 0.85 | TSHR (0.59) | TSHRTHRATHRBSMPD1MTNR1A | |
| SCHEMBL7460286 | 0.85 | TSHR (0.59) | TSHRTHRATHRBSMPD1MTNR1A | |
| SCHEMBL11435096 | 0.85 | APP (0.54) | TSHRAPPMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604363-B1 | Stable solutions of accelerators for epoxy resins | VANTICO AG (CH) | 2003-02-12 | — | — | EP | claimed |