Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.68 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.68 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.67 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.67 |
| ▸ | ANPEP | P15144 | 1/20 | 0.65 |
| ▸ | DPP4 | P27487 | 2/20 | 0.63 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.63 |
| ▸ | TGM2 | P21980 | 1/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486168 | 1.00 | DPP8 (0.68) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| SCHEMBL27502334 | 1.00 | DPP8 (0.68) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| SCHEMBL21219282 | 1.00 | DPP8 (0.68) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| SCHEMBL7019726 | 1.00 | DPP8 (0.68) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| SCHEMBL7025382 | 1.00 | DPP8 (0.68) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| SCHEMBL464672 | 0.99 | DPP8 (0.69) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| SCHEMBL5816135 | 0.99 | DPP8 (0.69) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| SCHEMBL453671 | 0.99 | DPP8 (0.69) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| Hydrochloric Acid SCHEMBL7297967 | 0.97 | DPP8 (0.68) | DPP8DPP7SLC1A3SLC1A1ANPEP | |
| Hydrochloric Acid SCHEMBL18770783 | 0.97 | DPP8 (0.68) | DPP8DPP7SLC1A3SLC1A1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6517869-B1 | Coupling such as DNA, RNA, oligonucleotides, proteins, peptides or drugs to free amino group | EXPRESSION GENETICS, INC. | 2003-02-11 | — | — | US | disclosed |
| WO-2001097781-A1 | POSITIVELY CHARGED POLY[ALPHA-(OMEGA-AMINOALKYL) GLYCOLIC ACID] FOR THE DELIVERY OF A BIOACTIVE AGENT VIA TISSUE AND CELLULAR UPTAKE | EXPRESSION GENETICS, INC. (US) | 2001-12-27 | — | — | WO | disclosed |
| US-6267987-B1 | BIODEGRADABLE AMINOALKYL POLYLACTONE HAVING BIOLOGICALLY ACTIVE MOIETIES, SUCH AS CARBOHYDRATES, PEPTIDES AND DRUGS, COUPLED TO FREE AMINO GROUPS | SAMYANG CORPORATION (KR) | 2001-07-31 | — | — | US | disclosed |
| WO-1999029758-A1 | POSITIVELY-CHARGED POLY[ALPHA-(OMEGA-AMINOALKYL)GLYCOLIC ACID] FOR THE DELIVERY OF A BIOACTIVE AGENT VIA TISSUE AND CELLULAR UPTAKE | SAMYANG CORPORATION (KR) | 1999-06-17 | — | — | WO | disclosed |