SCHEMBL464672

SCHEMBL464672

NC(CCCCNC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 3/20 0.69
DPP7 Q9UHL4 3/20 0.69
SLC1A3 P43003 1/20 0.69
SLC1A1 P43005 1/20 0.69
ANPEP P15144 1/20 0.67
DPP4 P27487 2/20 0.64
DPP9 Q86TI2 2/20 0.64
FOLH1 Q04609 4/20 0.62
HTT P42858 1/20 0.62
TGM2 P21980 1/20 0.59
MMP2 P08253 1/20 0.58
MMP9 P14780 1/20 0.58
LMNA P02545 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
KEAP1 Q14145 1/20 0.56
NFE2L2 Q16236 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL453671 1.00 DPP8 (0.69) DPP8DPP7SLC1A3SLC1A1ANPEP
SCHEMBL5816135 1.00 DPP8 (0.69) DPP8DPP7SLC1A3SLC1A1ANPEP
SCHEMBL7028548 0.99 DPP8 (0.68) DPP8DPP7SLC1A3SLC1A1ANPEP
Hydrochloric Acid SCHEMBL7297967 0.99 DPP8 (0.68) DPP8DPP7SLC1A3SLC1A1ANPEP
Hydrochloric Acid SCHEMBL31717958 0.99 DPP8 (0.68) DPP8DPP7SLC1A3SLC1A1ANPEP
SCHEMBL7025382 0.99 DPP8 (0.68) DPP8DPP7SLC1A3SLC1A1ANPEP
Hydrochloric Acid SCHEMBL18770783 0.99 DPP8 (0.68) DPP8DPP7SLC1A3SLC1A1ANPEP
SCHEMBL7019726 0.99 DPP8 (0.68) DPP8DPP7SLC1A3SLC1A1ANPEP
SCHEMBL21219282 0.99 DPP8 (0.68) DPP8DPP7SLC1A3SLC1A1ANPEP
SCHEMBL27502334 0.99 DPP8 (0.68) DPP8DPP7SLC1A3SLC1A1ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116601297-A Modified helicase and application thereof 北京齐碳科技有限公司 2023-08-15 CN claimed
CN-114599666-A Pif1-like helicase and application thereof 北京齐碳科技有限公司 2022-06-07 CN claimed
CN-113930406-A Pif1-like helicase and application thereof 北京齐碳科技有限公司 2022-01-14 CN claimed
US-20190127488-A1 ANTIBODY WITH NON-NATURAL AMINO ACID INTRODUCED THEREIN RIKEN (JP) 2019-05-02 US claimed
US-20260109724-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2026-04-23 US disclosed
EP-4702157-A1 ACYL-TRNA SYNTHETASES United Kingdom Research and Innovation (GB) 2026-03-04 EP disclosed
EP-4702156-A1 TRNA-BASED METHODS AND RELATED COMPOSITIONS United Kingdom Research and Innovation (GB) 2026-03-04 EP disclosed
US-20260021190-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES MERCK SHARP & DOHME LLC (US) 2026-01-22 US disclosed
US-12521437-B2 IL-2 conjugates and methods of use thereof Synthorx, Inc. (US) 2026-01-13 US disclosed
US-12491254-B2 Interleukin 10 conjugates and uses thereof Synthorx, Inc. (US) 2025-12-09 US disclosed
US-20250353833-A1 DPP9 BINDING COMPOUNDS UNIV ANTWERPEN (BE) 2025-11-20 US disclosed
US-20250325633-A1 CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES Synthorx, Inc. (US) 2025-10-23 US disclosed
EP-1569912-A2 2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2005-09-07 EP disclosed
WO-2004050637-A2 2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2004-06-17 WO disclosed
US-6294674-B1 FOR THERAPY OF MULTIPLE SCLEROSIS, ATHEROSCLEROTIC PLAQUE RUPTURE, RESTENOSIS, AORTIC ANEURISM, HEART FAILURE, PERIODONTAL DISEASE, CORNEAL ULCERATION, BURNS, DECUBITAL ULCERS, CHRONIC ULCERS OR WOUNDS, CANCER METASTASIS WARNER-LAMBERT COMPANY 2001-09-25 US disclosed
EP-0680469-B1 AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME BOEHRINGER INGELHEIM PHARMA (DE) 2000-04-26 EP disclosed
US-5948925-A Cationic amphiphiles containing linkers derived from neutral or positively charged amino acids GENZYME CORPORATION (US) 1999-09-07 US disclosed
EP-0929542-A1 COMPOUNDS FOR AND A METHOD OF INHIBITING MATRIX METALLOPROTEINASES WARNER-LAMBERT COMPANY (US) 1999-07-21 EP disclosed
WO-1998050418-A1 CATIONIC AMPHIPHILES CONTAINING LINKERS DERIVED FROM NEUTRAL OR POSITIVELY CHARGED AMINO ACIDS GENZYME CORPORATION (US) 1998-11-12 WO disclosed
WO-1998009957-A1 COMPOUNDS FOR AND A METHOD OF INHIBITING MATRIX METALLOPROTEINASES WARNER-LAMBERT COMPANY (US) 1998-03-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12491254-B2 Interleukin 10 conjugates and uses thereof IL2, CCR10, IL2RA DPP8 726/4885DPP7 1014/4885SLC1A3 3269/4885
US-20250325633-A1 CYTOKINE CONJUGATES FOR THE TREATMENT OF AUTOIMMUNE DISEASES IL2, IL2RA, IL15 DPP8 712/4885DPP7 354/4885SLC1A3 3456/4885
US-20260109724-A1 ANTIVIRAL COMPOUNDS IRF3, IFNAR1, HAVCR2 DPP8 466/4885DPP7 795/4885SLC1A3 3351/4885
US-20260021190-A1 GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A PENTA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES INSR, GPR119, GLP1R DPP8 38/4885DPP7 27/4885SLC1A3 1351/4885
US-20190127488-A1 ANTIBODY WITH NON-NATURAL AMINO ACID INTRODUCED THEREIN NSUN3, NSUN2, LNPEP DPP8 2708/4885DPP7 2957/4885SLC1A3 363/4885
US-20250353833-A1 DPP9 BINDING COMPOUNDS DPP9, DPP7, DPP3 DPP8 5/4885DPP7 2/4885SLC1A3 2525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.