Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 3/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8387914 | 1.00 | KDM5A (0.34) | KDM5AKDM4CKDM5BCTSCCTSK | |
| SCHEMBL7033118 | 0.91 | KDM5A (0.33) | KDM5AKDM4CKDM5BCTSCCTSK | |
| SCHEMBL8390265 | 0.91 | KDM5A (0.33) | KDM5AKDM4CKDM5BCTSCCTSK | |
| SCHEMBL8388235 | 0.90 | KDM5A (0.33) | KDM5AKDM4CKDM5B | |
| SCHEMBL7026537 | 0.90 | KDM5A (0.33) | KDM5AKDM4CKDM5B | |
| SCHEMBL7028362 | 0.88 | KDM5A (0.35) | KDM5AKDM4CKDM5BCTSCCTSK | |
| SCHEMBL8390301 | 0.88 | KDM5A (0.35) | KDM5AKDM4CKDM5BCTSCCTSK | |
| SCHEMBL8385781 | 0.84 | KDM5A (0.37) | KDM5AKDM4CKDM5BCTSCCTSK | |
| SCHEMBL8390577 | 0.84 | KDM5A (0.35) | KDM5AKDM4CKDM5BCTSCCTSK | |
| SCHEMBL8387042 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |