SCHEMBL8388235

SCHEMBL8388235

CC/C=C/C1CCC([C@H]2CC[C@H](c3ccc(COCC)c(F)c3)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
KDM5B Q9UGL1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7026537 1.00 KDM5A (0.33) KDM5AKDM4CKDM5B
SCHEMBL7025812 0.91 KDM5A (0.32) KDM5AKDM4CKDM5B
SCHEMBL8385724 0.91 KDM5A (0.32) KDM5AKDM4CKDM5B
SCHEMBL8387914 0.90 KDM5A (0.34) KDM5AKDM4CKDM5B
SCHEMBL7028645 0.90 KDM5A (0.34) KDM5AKDM4CKDM5B
SCHEMBL7033040 0.86 KDM5A (0.34) KDM5AKDM4CKDM5B
SCHEMBL8387253 0.86 KDM5A (0.34) KDM5AKDM4CKDM5B
SCHEMBL8726868 0.85 KDM5A (0.32) KDM5AKDM4CKDM5B
SCHEMBL8726877 0.85 KDM5A (0.32) KDM5AKDM4CKDM5B
SCHEMBL8726883 0.85 KDM5A (0.32) KDM5AKDM4CKDM5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5888423-A Fluorobenzyl ether derivatives ROLIC AG (CH) 1999-03-30 US disclosed