Butyric Acid

Butyric Acid

SCHEMBL7029284

CCCC(=O)O.CO.O=CO.c1ccccc1

nearest known ligand 0.65

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.65
HDAC3 O15379 1/20 0.65
HDAC1 Q13547 1/20 0.65
HDAC2 Q92769 1/20 0.65
HDAC8 Q9BY41 1/20 0.65
AKR1B1 P15121 1/20 0.44
PPARG P37231 10/20 0.42
PPARD Q03181 9/20 0.42
PPARA Q07869 9/20 0.42
GPR84 Q9NQS5 7/20 0.42
HDAC11 Q96DB2 5/20 0.42
TSHR P16473 4/20 0.42
PTPN1 P18031 3/20 0.42
ALDH1A1 P00352 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
FABP4 P15090 3/20 0.42
FFAR1 O14842 3/20 0.42
TLR2 O60603 2/20 0.42
MEN1 O00255 2/20 0.42
ESR1 P03372 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyric Acid SCHEMBL1257810 0.92
Butyric Acid SCHEMBL10338134 0.92 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL15261051 0.92 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL11243328 0.90 FFAR3 (0.72) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL30532231 0.90 FFAR3 (0.72) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL11484161 0.89 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL1257693 0.87 FFAR3 (0.68) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL11626724 0.87 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL11626727 0.87 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL1994703 0.87 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040265397-A1 Herbal composition for treatment of chronic renal failure and method to produce thereof JIANGSU KANION PHARMACEUTICAL CO., LTD. (CN) 2004-12-30 US claimed