Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16181522 | 0.81 | CYP1A2 (0.60) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL3645769 | 0.79 | ALDH1A1 (0.59) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL16181222 | 0.74 | CYP1A2 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6973848 | 0.73 | TSHR (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL124590 | 0.72 | ALDH1A1 (0.63) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL16181224 | 0.72 | ALDH1A1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL4043187 | 0.71 | ALDH1A1 (0.57) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL457530 | 0.71 | KAT2B (0.36) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP2D6 | |
| SCHEMBL11153835 | 0.70 | MAPT (0.33) | ALDH1A1CYP2D6CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL12978933 | 0.70 | ALDH1A1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276749-A1 | NOVEL, PHOTO-LABILE CUMARINYLMETHYL ESTERS OF CYCLIC NUCLEOTIDES, METHOD FOR THE PRODUCTION AND USE THEREOF | Forschungsverbund Berlin e.V. (DE) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001081360-A1 | NOVEL, PHOTO-LABILE CUMARINYLMETHYL ESTERS OF CYCLIC NUCLEOTIDES, METHOD FOR THE PRODUCTION AND USE THEREOF | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2001-11-01 | — | — | WO | disclosed |