Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409948 | 0.93 | TDP1 (0.42) | FAAHTDP1MEN1KMT2AMAPT | |
| SCHEMBL10017368 | 0.87 | TDP1 (0.50) | ZDHHC7TDP1MEN1KMT2AGPR84 | |
| SCHEMBL7508355 | 0.87 | TDP1 (0.50) | ZDHHC7TDP1MEN1KMT2AGPR84 | |
| SCHEMBL5860379 | 0.87 | TDP1 (0.50) | ZDHHC7TDP1MEN1KMT2AGPR84 | |
| SCHEMBL6828633 | 0.87 | TDP1 (0.50) | ZDHHC7TDP1MEN1KMT2AGPR84 | |
| SCHEMBL182928 | 0.87 | TDP1 (0.50) | ZDHHC7TDP1MEN1KMT2AGPR84 | |
| SCHEMBL4416096 | 0.87 | TDP1 (0.50) | ZDHHC7TDP1MEN1KMT2AGPR84 | |
| SCHEMBL9116048 | 0.87 | TDP1 (0.50) | ZDHHC7TDP1MEN1KMT2AGPR84 | |
| SCHEMBL2948251 | 0.87 | TDP1 (0.50) | ZDHHC7TDP1MEN1KMT2AGPR84 | |
| SCHEMBL5849644 | 0.87 | TDP1 (0.50) | ZDHHC7TDP1MEN1KMT2AGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889884-B1 | 1,2,4-TRIAZINE DERIVATIVES FOR THE INHIBITION OF PROTEIN GLYCOSYLATION | ALTEON INC (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6380192-B1 | FOR INHIBITING NONENZYMATIC CROSS-LINKING (PROTEIN AGING) | ALTEON, INC. | 2002-04-30 | — | — | US | disclosed |
| US-6060470-A | Triazine compounds and methods of use therefor | ALTEON, INC. | 2000-05-09 | — | — | US | disclosed |
| US-5932578-A | CAPABLE OF INHIBITING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS OF TARGET PROTEINS. FOOD SPOILAGE AND ANIMAL PROTEIN AGING CAN BE TREATED. | ALTEON INC. (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0889884-A1 | 1,2,4-TRIAZINE DERIVATIVES FOR THE INHIBITION OF PROTEIN GLYCOSYLATION | ALTEON, INC. (US) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997035849-A1 | 1,2,4-TRIAZINE DERIVATIVES FOR THE INHIBITION OF PROTEIN GLYCOSYLATION | ALTEON INC. (US) | 1997-10-02 | — | — | WO | disclosed |