Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 3/20 | 0.56 |
| ▸ | APAF1 | O14727 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.56 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.56 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | FAP | Q12884 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099242 | 0.89 | TDP1 (0.59) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL5099431 | 0.87 | TDP1 (0.76) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL5096480 | 0.87 | TDP1 (0.76) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL27458266 | 0.87 | TDP1 (0.76) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL5105288 | 0.87 | TDP1 (0.76) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL5105299 | 0.85 | NR1I2 (0.68) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL5138551 | 0.82 | TDP1 (0.65) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Cefcapene SCHEMBL419453 | 0.81 | FAP (0.77) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Cefcapene SCHEMBL419454 | 0.81 | FAP (0.77) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Cefcapene SCHEMBL419455 | 0.81 | FAP (0.77) | TDP1MAPTABCC4CNR1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824535-B1 | ANTIBACTERIAL CEPHALOSPORINS | BIOCHEMIE GMBH (AT) | 2003-02-26 | — | — | EP | disclosed |
| EP-1221446-A1 | Antibacterial cephalosporins | BIOCHEMIE Gesellschaft m.b.H. (AT) | 2002-07-10 | — | — | EP | disclosed |