Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE8B | O95263 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16551796 | 0.90 | ATM (0.40) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL16538597 | 0.90 | ATM (0.40) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL16538787 | 0.90 | ATM (0.40) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL16538727 | 0.90 | ATM (0.40) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL16551798 | 0.85 | ATM (0.40) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL16551813 | 0.85 | ATM (0.40) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL9972616 | 0.82 | ATM (0.40) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL9972609 | 0.82 | ATM (0.40) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL16538557 | 0.81 | ATM (0.41) | ALDH1A1MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL16538901 | 0.81 | ATM (0.41) | ALDH1A1MEN1KMT2AL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920441-B1 | 7ALPHA-(EPSILON-AMINOALKYL)-ESTRATRIENES, PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 7ALPHA-(EPSILON-AMINOALKYL)-ESTRATRIENES AND THEIR USE FOR PREPARING MEDICAMENT | SCHERING AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6271403-B1 | PURE ANTIESTROGENS, OR ESTROGENIC ANTIESTROGENS WITH ESTROGENIC PARTIAL ACTION. | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| US-5986115-A | STEROIDS WITH FLUORO GROUPS AND ETHER OR ESTER GROUPS | SCHERING AG (DE) | 1999-11-16 | — | — | US | disclosed |
| US-5866560-A | ESTROGEN INHIBITORS; TUMOR THERAPY; HORMONE REPLACEMENT THERAPY | SCHERING AG (DE) | 1999-02-02 | — | — | US | disclosed |