Succinimide

Succinimide

SCHEMBL7029968

CCCC(=O)O.O=C1CCC(=O)N1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.56
HDAC3 O15379 1/20 0.56
HDAC1 Q13547 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
CRBN Q96SW2 2/20 0.48
AKR1B1 P15121 1/20 0.39
HSD17B10 Q99714 2/20 0.38
GPR84 Q9NQS5 7/20 0.38
PPARG P37231 7/20 0.38
PPARD Q03181 7/20 0.38
PPARA Q07869 7/20 0.38
HDAC11 Q96DB2 5/20 0.38
TSHR P16473 4/20 0.38
PTPN1 P18031 3/20 0.38
ALDH1A1 P00352 2/20 0.38
TLR2 O60603 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
FABP4 P15090 2/20 0.38
SLC22A6 Q4U2R8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinimide SCHEMBL28354892 1.00 FFAR3 (0.56) FFAR3HDAC3HDAC1HDAC2HDAC8
Succinimide SCHEMBL28398892 0.94 FFAR3 (0.50) FFAR3HDAC3HDAC1HDAC2HDAC8
Valeric Acid SCHEMBL14334833 0.88 AKR1B1 (0.52) CRBNAKR1B1HSD17B10GPR84PPARG
Succinic Acid SCHEMBL27747025 0.86 CRBN (0.58) FFAR3HDAC3HDAC1HDAC2HDAC8
Succinic Acid SCHEMBL436244 0.86 CRBN (0.58) FFAR3HDAC3HDAC1HDAC2HDAC8
Hexanoate SCHEMBL8761793 0.86 AKR1B1 (0.61) AKR1B1HSD17B10GPR84PPARGPPARD
Palmitic Acid SCHEMBL23529891 0.84 GPR84 (0.63) AKR1B1HSD17B10GPR84PPARGPPARD
Stearic Acid SCHEMBL7117718 0.84 GPR84 (0.63) AKR1B1HSD17B10GPR84PPARGPPARD
Undecanoate SCHEMBL1465216 0.84 GPR84 (0.63) AKR1B1HSD17B10GPR84PPARGPPARD
Nonanoate SCHEMBL29126342 0.84 GPR84 (0.63) AKR1B1HSD17B10GPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115721730-A Pegylated vascular endothelial inhibin analogs and uses thereof 北京普罗吉生物科技发展有限公司 2023-03-03 CN claimed
CN-109963597-B Pegylated endostatin analogs and uses thereof 北京普罗吉生物科技发展有限公司 2022-08-26 CN claimed
CN-119816334-A Sealant for tissue closure 爱惜康股份有限公司 2025-04-11 CN disclosed
CN-119780422-A Alkaline phosphatase antibody marker, preparation method thereof, detection reagent and kit 深圳市锦瑞生物科技股份有限公司 2025-04-08 CN disclosed
WO-2024017379-A1 PREPARATION METHOD FOR POLYETHYLENE GLYCOL CONJUGATE OF ACTIVE POLYPEPTIDE OR PROTEIN 派格生物医药(苏州)股份有限公司 2024-01-25 WO disclosed
CN-116916969-A Novel conjugates of immunostimulatory IL-2 analogues and methods of making the same 韩美药品株式会社 2023-10-20 CN disclosed
CN-116724060-A Compositions and methods for modulating SIRPalpha-mediated signaling 小利兰·斯坦福大学董事会 2023-09-08 CN disclosed
CN-116648260-A Compositions and methods for inhibiting natural killer cell receptors 小利兰·斯坦福大学董事会 2023-08-25 CN disclosed
CN-116635050-A Novel triple agonists active on all of glucagon, GLP-1 and GIP receptors and uses thereof 韩美药品株式会社 2023-08-22 CN disclosed
CN-116615254-A Use of trigonometric agonists active on all of glucagon, GLP-1 and GIP receptors for the treatment of sequelae of respiratory tract infectious diseases 韩美药品株式会社 2023-08-18 CN disclosed
CN-116615240-A Engineered interleukin-10 polypeptides and uses thereof 小利兰·斯坦福大学董事会 2023-08-18 CN disclosed
CN-1897976-A Antagonists of the bradykinin b1 receptor AMGEN INC (US) 2007-01-17 CN disclosed
CN-1852740-A Prodrugs of highly branched polymers NEKTAR THERAPEUTICS AL CORP (US) 2006-10-25 CN disclosed
CN-1777440-A Method for preparing site-specific protein conjugate PR PHARMACEUTICALS INC (US) 2006-05-24 CN disclosed
CN-1747748-A Polymer derivatives having particular atom arrangements NEKTAR THERAPEUTICS AL CORP (US) 2006-03-15 CN disclosed
CN-1738640-A Interferon-alpha polypeptides and conjugates MAXYGEN INC (US) 2006-02-22 CN disclosed
EP-1284743-A2 PREPARATION OF A PATHOGEN INACTIVATED SOLUTION OF RED BLOOD CELLS HAVING REDUCED IMMUNOGENICITY Cerus Corporation (US) 2003-02-26 EP disclosed
US-20020042043-A1 Preparation of a pathogen inactivated solution of red blood cells having reduced immunogenicity STASSINOPOULOS ADONIS (US) 2002-04-11 US disclosed
WO-2001091775-A2 PREPARATION OF A PATHOGEN INACTIVATED SOLUTION OF RED BLOOD CELLS HAVING REDUCED IMMUNOGENICITY CERUS CORPORATION (US) 2001-12-06 WO disclosed
CN-1251133-A Bifunctional or multifunctional molecules based on dendroaspin scaffolds TRIGEN LTD (GB) 2000-04-19 CN disclosed