Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424555 | 0.83 | HSD17B10 (0.49) | HSD17B10CA1CA2RXRARXRB | |
| SCHEMBL11582054 | 0.83 | SMN1; SMN2 (0.45) | HTTELANESMN1; SMN2KMT2AESR1 | |
| SCHEMBL19847792 | 0.82 | HSD17B10 (0.49) | HSD17B10CA1CA2RXRARXRB | |
| SCHEMBL21237876 | 0.81 | HSD17B10 (0.44) | HSD17B10CA1CA2RXRARXRB | |
| SCHEMBL21237896 | 0.81 | HSD17B10 (0.44) | HSD17B10CA1CA2RXRARXRB | |
| SCHEMBL9724065 | 0.80 | SMN1; SMN2 (0.41) | HTTELANESMN1; SMN2KMT2AESR1 | |
| SCHEMBL5690655 | 0.79 | KMT2A (0.72) | HSD17B10CA1CA2RXRARXRB | |
| SCHEMBL11582556 | 0.78 | F3 (0.60) | KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL11032181 | 0.76 | KMT2A (0.51) | SMN1; SMN2KMT2AALDH1A1RAB9A | |
| SCHEMBL4366283 | 0.76 | HSD17B10 (0.53) | HSD17B10CA1CA2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736526-B1 | Pyrazolidine derivative, radical scavenger, brain-infarction depressant, and brain-edema depressant | SHISEIDO CO LTD (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-5849930-A | Pyrazolidine derivative radical scavenger brain-infarction depressant and brain-edema depressant | SHISEIDO CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0736526-A1 | Pyrazolidine derivative, radical scavenger, brain-infarction depressant, and brain-edema depressant | SHISEIDO COMPANY LIMITED (JP) | 1996-10-09 | — | — | EP | disclosed |