Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11584102 | 0.86 | KMT2A (0.43) | SMN1; SMN2ALDH1A1RAB9ANPC1ELANE | |
| SCHEMBL11583299 | 0.85 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1RAB9ANPC1ELANE | |
| SCHEMBL11582054 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1RAB9ANPC1ELANE | |
| SCHEMBL7029995 | 0.80 | HSD17B10 (0.51) | SMN1; SMN2ALDH1A1RAB9ANPC1ELANE | |
| SCHEMBL9724066 | 0.71 | MAPT (0.50) | SMN1; SMN2ALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL3194897 | 0.70 | TDP1 (0.54) | SMN1; SMN2ALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL11582556 | 0.70 | F3 (0.60) | ALDH1A1RAB9ANPC1KMT2AMAPT | |
| SCHEMBL11323924 | 0.69 | HDAC3 (0.66) | ALDH1A1RAB9ANPC1RECQLMAPT | |
| SCHEMBL9364615 | 0.69 | CYSLTR2 (0.50) | KMT2AMAPT | |
| SCHEMBL11032181 | 0.68 | KMT2A (0.51) | SMN1; SMN2ALDH1A1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4074151-A | — | — | None | — | — | JP | disclosed |
| JP-H0474151-A | PRODUCTION OF PHENOXYCARBOXYLIC ACID DERIVATIVE | NIPPON ZEON CO LTD | 1992-03-09 | — | — | JP | disclosed |
| US-4085135-A | ANTIULCER | TAISHO PHARMACEUTICAL CO., LTD. (JA) | 1978-04-18 | — | — | US | disclosed |