SCHEMBL70306

SCHEMBL70306

COC(=O)c1cc2cccnc2cc1C(=O)OC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.65
HTT P42858 1/20 0.65
PDGFRB P09619 1/20 0.53
PDGFRA P16234 1/20 0.53
ALDH1A1 P00352 4/20 0.49
MAP2K1 Q02750 1/20 0.49
PLK1 P53350 1/20 0.49
KDM4E B2RXH2 4/20 0.48
TDP1 Q9NUW8 1/20 0.48
NPC1 O15118 2/20 0.47
MEN1 O00255 2/20 0.47
POLB P06746 2/20 0.47
MAPT P10636 2/20 0.47
KMT2A Q03164 2/20 0.47
RAB9A P51151 1/20 0.46
HPGD P15428 2/20 0.45
NPSR1 Q6W5P4 1/20 0.45
SLC40A1 Q9NP59 1/20 0.44
P2RY14 Q15391 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30905588 1.00 ALOX15 (0.65) ALOX15HTTPDGFRBPDGFRAALDH1A1
SCHEMBL30905576 0.94 ALOX15 (0.58) ALOX15HTTPDGFRBPDGFRAALDH1A1
SCHEMBL27402305 0.94 ALOX15 (0.58) ALOX15HTTPDGFRBPDGFRAALDH1A1
SCHEMBL23660918 0.89 ALOX15 (0.64) ALOX15HTTPDGFRBPDGFRAALDH1A1
SCHEMBL22659328 0.89 ALOX15 (0.64) ALOX15HTTPDGFRBPDGFRAALDH1A1
SCHEMBL28336290 0.89 ALOX15 (0.60) ALOX15HTTPDGFRBPDGFRAALDH1A1
SCHEMBL30616281 0.89 ALOX15 (0.64) ALOX15HTTPDGFRBPDGFRAALDH1A1
SCHEMBL13515363 0.88 ALOX15 (0.58) ALOX15HTTPDGFRBPDGFRAALDH1A1
SCHEMBL16914982 0.88 HTT (0.58) ALOX15HTTPDGFRBPDGFRAALDH1A1
SCHEMBL13515345 0.88 ALOX15 (0.58) ALOX15HTTPDGFRBPDGFRAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024112853-A1 COMPOUNDS THAT INHIBIT PKMYT1 EXELIXIS, INC. (US) 2024-05-30 WO disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-5283335-A Controlling (mono or di)cotyledenous plants AMERICAN CYANAMID COMPANY (US) 1994-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 ALOX15 1966/4885HTT 1871/4885PDGFRB 4203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.