Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.39 |
| ▸ | PLAU | P00749 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 5/20 | 0.37 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
| ▸ | PROC | P04070 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7033896 | 1.00 | KMT2A (0.46) | KMT2ACTRB1FNTAFNTBITGB3 | |
| Hydrochloric Acid SCHEMBL7439321 | 0.99 | KMT2A (0.45) | KMT2ACTRB1FNTAFNTBITGB3 | |
| Hydrochloric Acid SCHEMBL7439342 | 0.99 | KMT2A (0.45) | KMT2ACTRB1FNTAFNTBITGB3 | |
| SCHEMBL7033111 | 0.89 | ITGB3 (0.43) | KMT2AFNTAFNTBITGB3ITGA2B | |
| SCHEMBL7034269 | 0.89 | ITGB3 (0.43) | KMT2AFNTAFNTBITGB3ITGA2B | |
| SCHEMBL7433506 | 0.89 | KMT2A (0.45) | KMT2ACTRB1FNTAFNTBHDAC6 | |
| SCHEMBL7433517 | 0.89 | KMT2A (0.45) | KMT2ACTRB1FNTAFNTBHDAC6 | |
| Hydrochloric Acid SCHEMBL6701564 | 0.88 | ITGB3 (0.42) | KMT2AFNTAFNTBITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6701572 | 0.88 | ITGB3 (0.42) | KMT2AFNTAFNTBITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL8339715 | 0.87 | KMT2A (0.43) | KMT2AFNTAFNTBHDAC6F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823898-B1 | HYDANTOINE DERIVATIVES AS INTERMEDIATE PRODUCTS FOR ACTIVE PHARMACEUTICAL AGENTS | HOECHST AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| US-5939556-A | Hydantoin compounds, salts thereof, processes for their preparation, and processes for preparing pharmaceutically active compounds comprising them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-08-17 | — | — | US | disclosed |