Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 1/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836680 | 0.85 | ALDH2 (0.58) | ALDH2ALDH3A1MEN1KMT2AMAPT | |
| SCHEMBL6832877 | 0.77 | ALDH2 (0.51) | ALDH2ALDH3A1TSHRMAOB | |
| SCHEMBL14192627 | 0.76 | ALDH2 (0.51) | ALDH2ALDH3A1TSHRMAOB | |
| SCHEMBL13673041 | 0.76 | ALDH2 (0.50) | ALDH2ALDH3A1MEN1KMT2AMAPT | |
| SCHEMBL13389081 | 0.75 | ALDH2 (0.53) | ALDH2ALDH3A1MEN1KMT2AMAPT | |
| SCHEMBL6832714 | 0.74 | ALDH2 (0.51) | ALDH2ALDH3A1TSHRMAOB | |
| SCHEMBL15354652 | 0.72 | ALDH2 (0.50) | ALDH2ALDH3A1MEN1KMT2AMAPT | |
| SCHEMBL27762658 | 0.72 | MEN1 (0.32) | MEN1KMT2AMAPTALOX12TDP1 | |
| SCHEMBL13708741 | 0.72 | FABP4 (0.38) | MAPTALDH1A1CD44 | |
| SCHEMBL5799941 | 0.70 | ALDH2 (0.47) | ALDH2ALDH3A1ALDH1A1TSHRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102161653-A | Chromanylurea compounds that inhibit vanilloid receptor subtype 1 (vr1) receptor and uses thereof | ABBOTT LAB | 2011-08-24 | — | — | CN | disclosed |
| CN-101443327-A | Chromanylurea compounds that inhibit vanilloid receptor subtype 1(VR1) receptor and uses thereof | ABBOTT LAB (US) | 2009-05-27 | — | — | CN | disclosed |
| EP-1322308-A2 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | Durect Corporation (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002028366-A9 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | DURECT CORP (US) | 2003-02-13 | — | — | WO | disclosed |
| WO-2002028366-A2 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | DURECT CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |