Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.54 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.45 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.45 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.45 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794733 | 1.00 | SPHK2 (0.54) | SPHK2SPHK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8656543 | 0.99 | NPC1 (0.54) | SPHK2SPHK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7794731 | 0.91 | SPHK2 (0.54) | SPHK2SPHK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7031470 | 0.91 | SPHK2 (0.54) | SPHK2SPHK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8656540 | 0.89 | SMN1; SMN2 (0.54) | SPHK2SPHK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7795897 | 0.85 | MEN1 (0.50) | NPC1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL7792628 | 0.80 | SPHK2 (0.48) | SPHK2SPHK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6152612 | 0.78 | LMNA (0.55) | SMN1; SMN2LMNAALDH1A1POLBCYP1A2 | |
| SCHEMBL3957761 | 0.78 | LMNA (0.52) | SPHK2SPHK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6608685 | 0.78 | KDM4E (0.61) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583665-B1 | Pharmaceutical composition and method for treating hyperlipidemia and arteriosclerosis | FUJI PHOTO FILM CO LTD (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-5387600-A | Anticholesterol agents; antilipemic agents | FUJI PHOTO FILM CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| US-5387600-A | Anticholesterol agents; antilipemic agents | FUJI PHOTO FILM CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0583665-A2 | Pharmaceutical composition and method for treating hyperlipidemia and arteriosclerosis | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-23 | — | — | EP | disclosed |
| EP-0583665-A2 | Pharmaceutical composition and method for treating hyperlipidemia and arteriosclerosis | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-23 | — | — | EP | disclosed |
| US-4415650-A | VACUUM DEPOSITING AN ORGANIC AND AN INORGANIC COMPOUND ON A SUPPORT; THERMOSENSITIVITY; LASERS | FUJI PHOTO FILM CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
| US-4286045-A | A SUPPORT HAVING A LAYER OF A CHALCOGENIDE OF GERMANIUM DOPED WITH SILVER OR COPPER; STABILITY; LITHOGRAPHIC PRINTING PLATES | FUJI PHOTO FILM CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4198237-A | GERMANIUM SULFIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-04-15 | — | — | US | disclosed |
| US-4197124-A | SILVER OR COPPER AND SULFUR, SELENIUM OR TELLURIUM0 | FUJI PHOTO FILM CO., LTD. (JP) | 1980-04-08 | — | — | US | disclosed |
| US-4177072-A | HYDROPHILIC AND OLEOPHILIC AREAS | FUJI PHOTO FILM CO., LTD. (JP) | 1979-12-04 | — | — | US | disclosed |