Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390388 | 1.00 | CYP2C9 (0.34) | CYP2C9KDM5AKDM4CKDM5BMAPT | |
| SCHEMBL7034698 | 0.97 | KDM5A (0.33) | CYP2C9KDM5AKDM4CKDM5BMAPT | |
| SCHEMBL8387103 | 0.97 | KDM5A (0.33) | CYP2C9KDM5AKDM4CKDM5BMAPT | |
| SCHEMBL7024827 | 0.89 | CYP2C9 (0.34) | CYP2C9KDM5AKDM4CKDM5BMAPT | |
| SCHEMBL8387101 | 0.89 | CYP2C9 (0.34) | CYP2C9KDM5AKDM4CKDM5BMAPT | |
| SCHEMBL8389581 | 0.88 | KDM5A (0.32) | CYP2C9KDM5AKDM4CKDM5BMAPT | |
| SCHEMBL7032811 | 0.88 | KDM5A (0.32) | CYP2C9KDM5AKDM4CKDM5BMAPT | |
| SCHEMBL8390749 | 0.88 | KDM5A (0.38) | CYP2C9KDM5AKDM4CKDM5BESR2 | |
| SCHEMBL7028213 | 0.88 | KDM5A (0.38) | CYP2C9KDM5AKDM4CKDM5BESR2 | |
| SCHEMBL7033648 | 0.87 | KDM5A (0.33) | KDM5AKDM4CKDM5BESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |