Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.32 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034698 | 1.00 | KDM5A (0.33) | KDM5AKDM4CKDM5BCYP2C9MAPT | |
| SCHEMBL7031970 | 0.97 | CYP2C9 (0.34) | KDM5AKDM4CKDM5BCYP2C9MAPT | |
| SCHEMBL8390388 | 0.97 | CYP2C9 (0.34) | KDM5AKDM4CKDM5BCYP2C9MAPT | |
| SCHEMBL8389637 | 0.90 | CYP2C9 (0.34) | KDM5AKDM4CKDM5BCYP2C9MAPT | |
| SCHEMBL7033190 | 0.90 | CYP2C9 (0.34) | KDM5AKDM4CKDM5BCYP2C9MAPT | |
| SCHEMBL7032295 | 0.88 | KDM5A (0.31) | KDM5AKDM4CKDM5BCYP2C9MAPT | |
| SCHEMBL8389685 | 0.88 | KDM5A (0.31) | KDM5AKDM4CKDM5BCYP2C9MAPT | |
| SCHEMBL7029011 | 0.88 | CYP2C9 (0.35) | CYP2C9MAPTGAAMEN1KMT2A | |
| SCHEMBL7024037 | 0.87 | KDM5A (0.33) | KDM5AKDM4CKDM5B | |
| SCHEMBL8387265 | 0.87 | KDM5A (0.33) | KDM5AKDM4CKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5888423-A | Fluorobenzyl ether derivatives | ROLIC AG (CH) | 1999-03-30 | — | — | US | disclosed |