Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290284 | 0.87 | NPC1 (0.49) | L3MBTL1NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6247750 | 0.83 | PTPRA (0.51) | L3MBTL1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL6247756 | 0.83 | PTPRA (0.51) | L3MBTL1NPC1RAB9ASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL7897236 | 0.82 | PTPRA (0.50) | L3MBTL1NPC1RAB9ASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL28915552 | 0.82 | PTPRA (0.50) | L3MBTL1NPC1RAB9ASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL8389822 | 0.82 | PTPRA (0.50) | L3MBTL1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL21768281 | 0.79 | RAB9A (0.51) | L3MBTL1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21768282 | 0.79 | RAB9A (0.51) | L3MBTL1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29002157 | 0.79 | MAPK1 (0.63) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL28085745 | 0.79 | MAPK1 (0.63) | NPC1RAB9AALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1291341-A1 | COMPOUNDS EXHIBITING THROMBOPOIETIN-LIKE ACTIVITIES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-12 | — | — | EP | disclosed |