Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14397981 | 0.85 | ALDH1A1 (0.73) | ALDH1A1HPGDHTTNPSR1RAB9A | |
| SCHEMBL11883414 | 0.85 | ALDH1A1 (0.73) | ALDH1A1HPGDHTTNPSR1SMN1; SMN2 | |
| SCHEMBL29543730 | 0.84 | KMT2A (0.70) | ALDH1A1HPGDHTTNPSR1SMN1; SMN2 | |
| SCHEMBL111479 | 0.84 | KMT2A (0.70) | ALDH1A1HPGDHTTNPSR1SMN1; SMN2 | |
| SCHEMBL31541283 | 0.83 | ALDH1A1 (1.00) | ALDH1A1HPGDHTTNPSR1SMN1; SMN2 | |
| SCHEMBL11458326 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HPGDHTTNPSR1SMN1; SMN2 | |
| SCHEMBL29485041 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HPGDHTTNPSR1SMN1; SMN2 | |
| SCHEMBL8672570 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HPGDHTTNPSR1SMN1; SMN2 | |
| SCHEMBL10814639 | 0.83 | ALDH1A1 (1.00) | ALDH1A1HPGDHTTNPSR1SMN1; SMN2 | |
| SCHEMBL11303046 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HPGDHTTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563509-A | Target the delivering nucleic acid compound certainly of the reduction size of long non-coding RNA | 阿克赛医药公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-108135923-A | Target superoxide dismutase 1（SOD1）Nucleic acid molecules | 阿克赛医药公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107073294-A | Methods of treating aging and skin conditions using nucleic acids targeting TYR or MMP1 | 阿克赛医药公司 | 2017-08-18 | — | — | CN | disclosed |
| US-20030049807-A1 | Micro-organism possessing enantioselective and regioselective nitrile hydratase/amidase activities | INSTITUTO BIOCHIMICO ITALIANO GIOVANNI LOREZINI S.P.A. (IT) | 2003-03-13 | — | — | US | disclosed |
| EP-1291435-A2 | A micro-organism possessing enantioselective and regioselective nitrile hydratase/amidase activities | ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI S.p.A. (IT) | 2003-03-12 | — | — | EP | disclosed |