Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.50 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30446733 | 1.00 | PRMT6 (0.51) | PRMT6ADORA1P2RY12LMNAALDH1A1 | |
| SCHEMBL8937133 | 1.00 | PRMT6 (0.51) | PRMT6ADORA1P2RY12LMNAALDH1A1 | |
| SCHEMBL13020575 | 0.96 | MEN1 (0.50) | PRMT6ADORA1P2RY12LMNAALDH1A1 | |
| SCHEMBL26653470 | 0.96 | PRMT6 (0.49) | PRMT6ADORA1P2RY12LMNAALDH1A1 | |
| SCHEMBL30052580 | 0.94 | PRMT6 (0.48) | PRMT6ADORA1P2RY12LMNAALDH1A1 | |
| SCHEMBL29479254 | 0.94 | PRMT6 (0.52) | PRMT6ADORA1P2RY12LMNAALDH1A1 | |
| SCHEMBL29479246 | 0.94 | PRMT6 (0.52) | PRMT6ADORA1P2RY12LMNAALDH1A1 | |
| SCHEMBL1068383 | 0.94 | PRMT6 (0.48) | PRMT6ADORA1P2RY12LMNAALDH1A1 | |
| SCHEMBL18496436 | 0.94 | PRMT6 (0.48) | PRMT6ADORA1P2RY12LMNAALDH1A1 | |
| SCHEMBL18496435 | 0.94 | PRMT6 (0.48) | PRMT6ADORA1P2RY12LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303613-A1 | 3′3′ CYCLIC DINUCLEOTIDES WITH AN ALKENYLENE | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR, V.V.I. (CZ) | 2023-09-28 | — | — | US | disclosed |
| CN-111434671-A | Liver specificity AMPK agonist and preparation method and application thereof | 凯思凯迪（上海）医药科技有限公司 | 2020-07-21 | — | — | CN | disclosed |
| EP-0777485-B1 | 2',5' PHOSPHOROTHIOATE/PHOSPHODIESTER OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | UNIV TEMPLE (US) | 2003-02-19 | — | — | EP | disclosed |
| EP-0694559-B1 | 2',5'-Phosphorothioate oligoadenylates and antiviral uses thereof | UNIV TEMPLE (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5863905-A | GREATLY ENHANCED METABOLIC STABILITY; NONHYDROLYZING; RESISTANCE TO SERUM PHOSPHODIESTERASES; NONTOXIC; INHIBIT OR ACTIVATE RIBONUCLEASE; AIDS, HTLV; HEPATITIS VIRUS; MS; PLANT VIRUSES, E.G. TOBACCO MOSAIC VIRUS; | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1999-01-26 | — | — | US | disclosed |
| US-5556840-A | 2',5'-phosphorothioate oligoadenylates as anitiviral agents | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1996-09-17 | — | — | US | disclosed |
| EP-0389521-B1 | 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | UNIV TEMPLE (US) | 1996-03-20 | — | — | EP | disclosed |
| EP-0694559-A2 | 2',5'-Phosphorothioate oligoadenylates and antiviral uses thereof | Temple University of the Commonwealth System of Higher Education (US) | 1996-01-31 | — | — | EP | disclosed |
| US-5405939-A | viricides | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1995-04-11 | — | — | US | disclosed |
| US-5188897-A | Viricides, metabolic stability | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0389521-A4 | 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | — | 1992-02-05 | — | — | EP | disclosed |
| EP-0389521-A1 | 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | Temple University of the Commonwealth System of Higher Education (US) | 1990-10-03 | — | — | EP | disclosed |
| US-4924624-A | TOBACCO MOSAIC VIRUS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1990-05-15 | — | — | US | disclosed |
| WO-1989003683-A1 | 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HI (US) | 1989-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303613-A1 | 3′3′ CYCLIC DINUCLEOTIDES WITH AN ALKENYLENE | STING1, CGAS, IRF3 | PRMT6 1613/4885ADORA1 217/4885P2RY12 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.