SCHEMBL7032346

SCHEMBL7032346

CC(=O)NC1CC2CC=CC=C2S1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10667994 0.85
SCHEMBL11300278 0.82
SCHEMBL3643389 0.71
SCHEMBL16113551 0.70
SCHEMBL6657068 0.67 SMN1; SMN2 (0.31) SMN1; SMN2NPSR1
SCHEMBL3244590 0.66
SCHEMBL6763002 0.65 CYP1A2 (0.33)
SCHEMBL28096060 0.63
SCHEMBL14546306 0.62 CYP11B1 (0.33)
SCHEMBL13580124 0.61 SMN1; SMN2 (0.30) SMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1280792-A1 METHOD FOR PRODUCING BENZO ANNELATED HETEROCYCLES MERCK PATENT GmbH (DE) 2003-02-05 EP disclosed
WO-2001077099-A1 METHOD FOR PRODUCING BENZO ANNELATED HETEROCYCLES MERCK PATENT GMBH (DE) 2001-10-18 WO disclosed