Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343777 | 0.76 | ATM (0.43) | ATMCYP19A1PDGFRBPDGFRA | |
| SCHEMBL7365903 | 0.74 | ATM (0.44) | ATMCYP19A1MAPTPDGFRBPDGFRA | |
| SCHEMBL9261457 | 0.74 | ATM (0.44) | ATMCYP19A1MAPTPDGFRBPDGFRA | |
| SCHEMBL11006498 | 0.70 | DPP4 (0.36) | ATMCYP19A1 | |
| SCHEMBL7678699 | 0.70 | — | — | |
| SCHEMBL13006650 | 0.70 | — | — | |
| SCHEMBL14492515 | 0.70 | — | — | |
| SCHEMBL9077295 | 0.70 | — | — | |
| SCHEMBL13006656 | 0.70 | — | — | |
| SCHEMBL8294107 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1285014-A1 | DIMETHYLPYRAZOLE-BLOCKED ISOCYANATE MIXTURES | Bayer Aktiengesellschaft (DE) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001085823-A1 | DIMETHYLPYRAZOLE-BLOCKED ISOCYANATE MIXTURES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-11-15 | — | — | WO | disclosed |