SCHEMBL7365903

SCHEMBL7365903

C1CC2CC1CC2OC1CC2CCC1C2

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.44
CYP19A1 P11511 1/20 0.36
PDE4A P27815 3/20 0.33
PDE4B Q07343 3/20 0.33
PDE4C Q08493 3/20 0.33
PDE4D Q08499 3/20 0.33
PDGFRB P09619 2/20 0.33
PDGFRA P16234 2/20 0.33
MAPT P10636 1/20 0.31
POLB P06746 1/20 0.31
GRM1 Q13255 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15043146 0.82 ATM (0.35) ATMPDE4APDE4BPDE4CPDE4D
SCHEMBL9261457 0.82 ATM (0.44) ATMCYP19A1PDE4APDE4BPDE4C
SCHEMBL20798696 0.78 ALDH1A1 (0.40) ATMCYP19A1
SCHEMBL15466445 0.78 ALDH1A1 (0.40) ATMCYP19A1
SCHEMBL4200480 0.78
SCHEMBL9077295 0.78
SCHEMBL13006656 0.78
SCHEMBL13006650 0.78
SCHEMBL9261447 0.78 ATM (0.41) ATMCYP19A1PDGFRBPDGFRAPOLB
SCHEMBL7678699 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208718-A1 MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME MOMENTIVE PERFORMANCE MATERIALS INC. 2018-07-26 US claimed
EP-3325557-A1 MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME Momentive Performance Materials GmbH (DE) 2018-05-30 EP claimed
WO-2017012715-A1 MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2017-01-26 WO claimed
US-11814484-B2 Modified filler particles and silicone compositions comprising the same MOMENTIVE PERFORMANCE MATERIALS GMBH 2023-11-14 US disclosed
US-20220002492-A1 MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2022-01-06 US disclosed
US-11015024-B2 Modified filler particles and silicone compositions comprising the same MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2021-05-25 US disclosed
EP-3265430-B1 USE OF CRYSTALLINE TANTALUM OXIDE PARTICLES AS PINNING CENTER IN SUPERCONDUCTOR BASF SE (DE) 2019-06-05 EP disclosed
US-10233091-B2 Process for producing crystalline tantalum oxide particles BASF SE (DE) 2019-03-19 US disclosed
US-20180208718-A1 MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME MOMENTIVE PERFORMANCE MATERIALS INC. 2018-07-26 US disclosed
EP-3325557-A1 MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME Momentive Performance Materials GmbH (DE) 2018-05-30 EP disclosed
US-20180044199-A1 PROCESS FOR PRODUCING CRYSTALLINE TANTALUM OXIDE PARTICLES BASF SE (DE) 2018-02-15 US disclosed
US-5520710-A Cleaner burning and cetane enhancing diesel fuel supplements Olah, George A. (US) 1996-05-28 US disclosed
US-5459145-A Calcium independent camp phosphodiesterase inhibitor antidepressant PFIZER INC. (US) 1995-10-17 US disclosed
WO-1995025153-A1 CLEANER BURNING AND CETANE ENHANCING DIESEL FUEL SUPPLEMENTS OLAH GEORGE A (US) 1995-09-21 WO disclosed
US-5294730-A A-Amino-4-alkoxy-3-polycycloalkyloxybenzyl cyanide derivatives PFIZER INC. (US) 1994-03-15 US disclosed
EP-0247725-B1 Calcium independent camp phosphodiestrerase inhibitor antidepressant PFIZER (US) 1994-03-02 EP disclosed
US-5196426-A CALCIUM INDEPENDENT C AMP PHOSPHODIESTERASE INHIBITOR ANTIDEPRESSANT PFIZER INC. (US) 1993-03-23 US disclosed
US-5128358-A Aryl substituted nitrogen heterocyclic antidepressants PFIZER INC. (US) 1992-07-07 US disclosed
EP-0247725-A2 Calcium independent camp phosphodiestrerase inhibitor antidepressant PFIZER INC. (US) 1987-12-02 EP disclosed
WO-1987006576-A1 CALCIUM INDEPENDENT CAMP PHOSPHODIESTERASE INHIBITOR ANTIDEPRESSANT PFIZER INC. (US) 1987-11-05 WO disclosed