SCHEMBL7033150

SCHEMBL7033150

Brc1ccc(N(c2ccccc2)c2ccccc2)cc1.Brc1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.56
TDP1 Q9NUW8 3/20 0.56
L3MBTL1 Q9Y468 3/20 0.56
MAPT P10636 2/20 0.56
KDM4E B2RXH2 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
CYP2C19 P33261 1/20 0.56
MAPK1 P28482 2/20 0.50
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CRHBP P24387 1/20 0.46
ATM Q13315 1/20 0.46
CRHR2 Q13324 1/20 0.46
TLR9 Q9NR96 1/20 0.46
CYP2A6 P11509 1/20 0.44
TSHR P16473 2/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL680815 1.00 ALDH1A1 (0.56) ALDH1A1TDP1L3MBTL1MAPTKDM4E
SCHEMBL460304 1.00 ALDH1A1 (0.56) ALDH1A1TDP1L3MBTL1MAPTKDM4E
SCHEMBL15687666 1.00 ALDH1A1 (0.56) ALDH1A1TDP1L3MBTL1MAPTKDM4E
SCHEMBL13721434 1.00 ALDH1A1 (0.56) ALDH1A1TDP1L3MBTL1MAPTKDM4E
SCHEMBL24576 1.00 ALDH1A1 (0.56) ALDH1A1TDP1L3MBTL1MAPTKDM4E
SCHEMBL15907013 1.00 ALDH1A1 (0.56) ALDH1A1TDP1L3MBTL1MAPTKDM4E
SCHEMBL13969319 0.93 ALDH1A1 (0.64) ALDH1A1TDP1L3MBTL1MAPTKDM4E
SCHEMBL74527 0.93 ALDH1A1 (0.64) ALDH1A1TDP1L3MBTL1MAPTKDM4E
SCHEMBL18533157 0.93 ALDH1A1 (0.64) ALDH1A1TDP1L3MBTL1MAPTKDM4E
SCHEMBL20664596 0.93 ALDH1A1 (0.64) ALDH1A1TDP1L3MBTL1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6682782-B2 TRANSISTORS, LIQUID CRYSTAL DISPLAY, ELECTROOPTICS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2004-01-27 US disclosed
US-20020018912-A1 Organic compound having an acetylene group, vacuum deposition polymerization thereof, deposited polymerized thin film, and electroluminescence device containing same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2002-02-14 US disclosed
EP-1170273-A1 Alkynic compounds, their use as monomers in vacuum deposition polymerisation, thin films formed from these polymers and their use in electroluminescent devices KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2002-01-09 EP disclosed