Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030425 | 0.93 | EGFR (0.32) | EGFRERBB2 | |
| SCHEMBL7020871 | 0.87 | EGFR (0.36) | EGFRERBB2 | |
| SCHEMBL7023727 | 0.87 | EGFR (0.37) | EGFRERBB2 | |
| SCHEMBL7639926 | 0.85 | EGFR (0.38) | EGFRERBB2 | |
| SCHEMBL7026841 | 0.84 | EGFR (0.33) | EGFRERBB2 | |
| SCHEMBL7027701 | 0.84 | MEN1 (0.32) | EGFRERBB2 | |
| SCHEMBL7033389 | 0.84 | EGFR (0.35) | EGFRERBB2 | |
| SCHEMBL7027358 | 0.81 | EGFR (0.35) | EGFRERBB2 | |
| SCHEMBL7024459 | 0.81 | CA12 (0.33) | EGFRERBB2 | |
| SCHEMBL7023447 | 0.80 | LMNA (0.36) | EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064253-B1 | ANTI-TUMOUR AGENTS | ASTRAZENECA AB (SE) | 2003-01-29 | — | — | EP | claimed |
| US-6346633-B1 | TERT-AMINOPHENYLESTER OF ACID | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | claimed |
| EP-1064253-A1 | ANTI-TUMOUR AGENTS | AstraZeneca AB (SE) | 2001-01-03 | — | — | EP | claimed |
| WO-1999048857-A1 | ANTI-TUMOUR AGENTS | ASTRAZENECA AB (SE) | 1999-09-30 | — | — | WO | claimed |
| EP-1064253-B1 | ANTI-TUMOUR AGENTS | ASTRAZENECA AB (SE) | 2003-01-29 | — | — | EP | disclosed |
| US-6346633-B1 | TERT-AMINOPHENYLESTER OF ACID | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | disclosed |