Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027776 | 1.00 | CUL4A (0.46) | CUL4AALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL29512894 | 0.87 | CUL4A (0.49) | CUL4AALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL3435628 | 0.83 | ALDH1A1 (0.47) | CUL4AALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL4060044 | 0.83 | ALDH1A1 (0.47) | CUL4AALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL30789653 | 0.81 | CUL4A (0.42) | CUL4AALDH1A1KMT2AMCOLN3MAPT | |
| SCHEMBL5518635 | 0.78 | ALDH1A1 (0.48) | CUL4AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL29512788 | 0.78 | CUL4A (0.51) | CUL4AALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL29512840 | 0.78 | KMT2A (0.46) | CUL4AALDH1A1KMT2AMCOLN3MEN1 | |
| SCHEMBL30789585 | 0.77 | ALDH1A1 (0.40) | CUL4AALDH1A1MAPTLMNAGAA | |
| SCHEMBL2940730 | 0.75 | ACVR1 (0.41) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874852-B1 | OXAZOLIDINONE ANTIBACTERIAL AGENT WITH TRICYCLIC SUBSTITUENTS | UPJOHN CO (US) | 2004-03-31 | — | — | EP | disclosed |
| EP-0874852-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENT WITH TRICYCLIC SUBSTITUENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997019089-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENT WITH TRICYCLIC SUBSTITUENTS | PHARMACIA & UPJOHN COMPANY (US) | 1997-05-29 | — | — | WO | disclosed |