SCHEMBL7034541

SCHEMBL7034541

CCCC1=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc2C1CC1C(CCC)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.34
CREBBP Q92793 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7037709 0.92 BRD4 (0.34) BRD4CREBBP
SCHEMBL7198398 0.90 BRD4 (0.35) BRD4CREBBP
SCHEMBL3999811 0.88 BRD4 (0.32) BRD4CREBBP
SCHEMBL7035241 0.85 BRD4 (0.32) BRD4CREBBP
SCHEMBL7036203 0.85 BRD4 (0.32) BRD4CREBBP
Hydrochloric Acid SCHEMBL7200620 0.84 BRD4 (0.31) BRD4CREBBP
SCHEMBL7037878 0.82 NPC1 (0.33) BRD4CREBBP
Hydrochloric Acid SCHEMBL2526488 0.82 BRD4 (0.31) BRD4CREBBP
SCHEMBL7200621 0.82 BRD4 (0.31) BRD4CREBBP
SCHEMBL7105425 0.82 BRD4 (0.31) BRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6620953-B1 Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts BASSELL POLYOLEFINE GMBH (DE) 2003-09-16 US disclosed
EP-1133504-B1 METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES BASELL POLYOLEFINE GMBH (DE) 2003-03-12 EP disclosed