Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 2/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27464017 | 0.93 | BRD4 (0.30) | BRD4CREBBP | |
| Hydrochloric Acid SCHEMBL28753283 | 0.91 | KCNH2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL29695950 | 0.90 | BRD4 (0.34) | BRD4CREBBPKIF11PARP1 | |
| Hydrochloric Acid SCHEMBL6459366 | 0.90 | BRD4 (0.34) | BRD4CREBBPKIF11PARP1 | |
| Hydrochloric Acid SCHEMBL27464016 | 0.86 | SYK (0.32) | — | |
| Hydrochloric Acid SCHEMBL27479292 | 0.85 | ADRB2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL27543128 | 0.85 | EDNRB (0.34) | — | |
| Hydrochloric Acid SCHEMBL14812511 | 0.84 | NPC1 (0.33) | BRD4CREBBPKIF11 | |
| Hydrochloric Acid SCHEMBL2526488 | 0.84 | BRD4 (0.31) | BRD4CREBBP | |
| SCHEMBL7034541 | 0.84 | BRD4 (0.34) | BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167973-B | High purity polypropylene for molding and polypropylene composition | 道达尔研究技术弗吕公司 | 2022-06-17 | — | — | CN | disclosed |
| US-20030236378-A1 | For producing propylene polymers that are suited for fiber spinning | BASELL POLYOLEFINE GMBH (DE) | 2003-12-25 | — | — | US | disclosed |