Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 17/20 | 0.57 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029339 | 0.88 | STING1 (0.51) | STING1 | |
| SCHEMBL7033796 | 0.81 | STING1 (0.45) | STING1 | |
| SCHEMBL7032738 | 0.81 | STING1 (0.45) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7027417 | 0.80 | STING1 (0.50) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7028412 | 0.80 | STING1 (0.47) | STING1 | |
| SCHEMBL7029438 | 0.80 | MMP8 (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7032920 | 0.78 | STING1 (0.40) | STING1 | |
| SCHEMBL7028409 | 0.78 | STING1 (0.45) | STING1 | |
| SCHEMBL7033189 | 0.77 | STING1 (0.48) | STING1CNR2 | |
| SCHEMBL7032737 | 0.77 | STING1 (0.47) | STING1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284265-A1 | BENZOTHIOPHENE DERIVATIVES AND MEDICINAL USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2003-02-19 | — | — | EP | disclosed |