Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | RARB | P10826 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038794 | 0.95 | HSD11B1 (0.40) | HSD11B1RARBALDH1A1MAPTRAB9A | |
| SCHEMBL7039008 | 0.90 | S1PR1 (0.32) | HSD11B1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7039771 | 0.87 | HSD11B1 (0.37) | HSD11B1RARBHSD17B10ALDH1A1MEN1 | |
| SCHEMBL7201117 | 0.87 | HSD11B1 (0.40) | HSD11B1RARBHSD17B10ALDH1A1MEN1 | |
| SCHEMBL7031849 | 0.87 | HSD11B1 (0.37) | HSD11B1RARBHSD17B10ALDH1A1MEN1 | |
| SCHEMBL7198194 | 0.86 | HSD11B1 (0.40) | HSD11B1RARBHSD17B10ALDH1A1MEN1 | |
| SCHEMBL7037406 | 0.85 | HSD11B1 (0.36) | HSD11B1RARBHSD17B10ALDH1A1MEN1 | |
| SCHEMBL7037129 | 0.85 | EDNRB (0.35) | ALDH1A1MAPTKDM4EGAARAB9A | |
| 1-Hexanol SCHEMBL16353476 | 0.83 | SOAT1 (0.36) | — | |
| SCHEMBL7031378 | 0.83 | HSD11B1 (0.37) | HSD11B1RARBHSD17B10ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |
| EP-1133504-B1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | disclosed |