Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CD74 | P04233 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266678 | 0.86 | MEN1 (0.41) | SMN1; SMN2NPC1RAB9AMITFMEN1 | |
| SCHEMBL3241412 | 0.85 | SMN1; SMN2 (0.38) | SMN1; SMN2NPC1RAB9AMITFMEN1 | |
| SCHEMBL10841005 | 0.84 | NPC1 (0.39) | SMN1; SMN2NPC1RAB9AMITFMEN1 | |
| SCHEMBL1629578 | 0.81 | NPC1 (0.39) | SMN1; SMN2NPC1RAB9AMITFMEN1 | |
| SCHEMBL27711169 | 0.75 | P2RX4 (0.42) | SMN1; SMN2NPC1RAB9AMITFMEN1 | |
| SCHEMBL3375350 | 0.73 | BCHE (0.44) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL9938376 | 0.72 | NPC1 (0.38) | NPC1RAB9AMITFMEN1KMT2A | |
| SCHEMBL6980620 | 0.72 | POLB (0.54) | SMN1; SMN2KDM4EALDH1A1TSHRLMNA | |
| SCHEMBL6110762 | 0.72 | P2RX4 (0.46) | SMN1; SMN2NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL5670700 | 0.72 | BCHE (0.46) | MEN1KMT2ANOTUMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250334-B1 | Medicaments useful for the treatment of proliferative diseases | LILLY CO ELI (US) | 2004-05-19 | — | — | EP | disclosed |