Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036901 | 0.81 | PDE5A (0.39) | HSD11B1MAP3K12 | |
| SCHEMBL7112048 | 0.79 | PDE5A (0.39) | HSD11B1MAP3K12 | |
| SCHEMBL7038467 | 0.78 | HTR2A (0.34) | HTR2AHTR2CPOLB | |
| SCHEMBL7037908 | 0.78 | HTR2A (0.36) | HSD11B1HTR2AHTR2CPOLB | |
| SCHEMBL7039209 | 0.78 | PDE5A (0.39) | HSD11B1MAP3K12 | |
| SCHEMBL7035928 | 0.78 | PDE5A (0.39) | HSD11B1MAP3K12 | |
| SCHEMBL7040816 | 0.78 | PDE5A (0.39) | HSD11B1MAP3K12 | |
| SCHEMBL7040126 | 0.73 | PDE5A (0.38) | HSD11B1 | |
| SCHEMBL7037511 | 0.73 | PDE5A (0.38) | HSD11B1 | |
| SCHEMBL7037321 | 0.72 | PDE4B (0.40) | HSD11B1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003004494-A1 | PYRIDAZINONE COMPOUND AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-16 | — | — | WO | disclosed |