Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037908 | 0.81 | HTR2A (0.36) | HTR2AHTR2CPOLB | |
| SCHEMBL7039890 | 0.79 | PDE5A (0.42) | POLBTP53 | |
| SCHEMBL7035546 | 0.78 | HSD11B1 (0.32) | HTR2AHTR2CPOLB | |
| SCHEMBL7032843 | 0.70 | PDE5A (0.40) | POLB | |
| SCHEMBL7038474 | 0.70 | PDE5A (0.41) | POLBTP53 | |
| SCHEMBL7037944 | 0.68 | PDE5A (0.42) | POLBTP53 | |
| SCHEMBL6822091 | 0.65 | ADORA1 (0.41) | POLBTP53 | |
| SCHEMBL7033864 | 0.64 | ADORA1 (0.38) | — | |
| SCHEMBL7036909 | 0.64 | ADORA1 (0.43) | — | |
| SCHEMBL7036143 | 0.63 | PDE5A (0.39) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003004494-A1 | PYRIDAZINONE COMPOUND AS ADENOSINE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-01-16 | — | — | WO | disclosed |