Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNTT | P04053 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076557 | 0.98 | DNTT (0.37) | DNTTPOLBPOLA1ALDH1A1KMT2A | |
| SCHEMBL8709284 | 0.78 | — | — | |
| SCHEMBL12494483 | 0.78 | CYP2C19 (0.39) | POLBALDH1A1HTT | |
| SCHEMBL12467437 | 0.75 | DNTT (0.31) | DNTTPOLB | |
| SCHEMBL598037 | 0.75 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL19346720 | 0.74 | — | — | |
| SCHEMBL28750893 | 0.72 | ALDH1A1 (0.33) | POLBALDH1A1BRD4CYP1A2 | |
| SCHEMBL27590444 | 0.72 | ALDH1A1 (0.33) | POLBALDH1A1BRD4CYP1A2 | |
| SCHEMBL12870314 | 0.72 | ALDH1A1 (0.33) | POLBALDH1A1BRD4CYP1A2 | |
| SCHEMBL27608813 | 0.72 | ALDH1A1 (0.33) | POLBALDH1A1BRD4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1468677-B1 | An antireflux syrup | DMG ITALIA SRL (IT) | 2012-08-08 | — | — | EP | disclosed |
| EP-1468677-A2 | An antireflux syrup | D.M.G. Italia Srl (IT) | 2004-10-20 | — | — | EP | disclosed |