SCHEMBL7035838

SCHEMBL7035838

CON=C(C(N)=O)c1ccccc1CON=C(C)C1CC1c1c(F)cccc1F

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.38
MAPT P10636 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GPR88 Q9GZN0 1/20 0.33
KDM1A O60341 2/20 0.31
METAP2 P50579 2/20 0.31
KMT2A Q03164 1/20 0.31
PARP15 Q460N3 1/20 0.31
PARP10 Q53GL7 1/20 0.31
HNF4A P41235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6158177 1.00 HIF1A (0.38) HIF1AMAPTL3MBTL1GPR88KDM1A
SCHEMBL6156049 0.91 HIF1A (0.48) HIF1AMAPTL3MBTL1GPR88
SCHEMBL6156045 0.91 HIF1A (0.48) HIF1AMAPTL3MBTL1GPR88
SCHEMBL7707860 0.91 HIF1A (0.48) HIF1AMAPTL3MBTL1GPR88
SCHEMBL6155346 0.89 HIF1A (0.38) HIF1AMAPTL3MBTL1
SCHEMBL6155347 0.89 HIF1A (0.38) HIF1AMAPTL3MBTL1
SCHEMBL6227065 0.86 MAPK1 (0.42) HIF1AMAPTL3MBTL1METAP2KMT2A
SCHEMBL6227068 0.86 MAPK1 (0.42) HIF1AMAPTL3MBTL1METAP2KMT2A
SCHEMBL6227062 0.86 MAPK1 (0.42) HIF1AMAPTL3MBTL1METAP2KMT2A
SCHEMBL8096545 0.83 MAPT (0.50) HIF1AMAPTL3MBTL1GPR88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1286955-A1 ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES Dow AgroSciences LLC (US) 2003-03-05 EP disclosed
US-6348627-B1 CONTROLLING PHYTOPATHOGENIC FUNGI DOW AGROSCIENCES LLC 2002-02-19 US disclosed
WO-2001087826-A1 ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES ROHM AND HAAS COMPANY (US) 2001-11-22 WO disclosed