Pomolic Acid

Pomolic Acid

SCHEMBL7035935

C[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@@H](O)C(C)(C)C5CC[C@]43C)[C@@H]2[C@]1(C)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 8/20 1.00
SENP1 Q9P0U3 3/20 1.00
POLB P06746 4/20 0.73
PTPN2 P17706 4/20 0.73
AKR1B10 O60218 3/20 0.73
PTPRF P10586 3/20 0.73
CES1 P23141 3/20 0.73
ACP1 P24666 3/20 0.73
PTPN6 P29350 3/20 0.73
PTGS2 P35354 3/20 0.73
RELA Q04206 3/20 0.73
GPBAR1 Q8TDU6 3/20 0.73
USP7 Q93009 3/20 0.73
MEN1 O00255 2/20 0.73
KMT2A Q03164 2/20 0.73
USP2 O75604 2/20 0.73
HSD11B1 P28845 2/20 0.73
CTSD P07339 1/20 0.73
CYP19A1 P11511 1/20 0.73
CETP P11597 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pomolic Acid SCHEMBL7357945 1.00 PTPN1 (1.00) PTPN1SENP1POLBPTPN2AKR1B10
Pomolic Acid SCHEMBL829116 1.00 PTPN1 (1.00) PTPN1SENP1POLBPTPN2AKR1B10
Pomolic Acid SCHEMBL30417300 1.00 PTPN1 (1.00) PTPN1SENP1POLBPTPN2AKR1B10
Epipomolic Acid SCHEMBL7035933 1.00 PTPN1 (1.00) PTPN1SENP1POLBPTPN2AKR1B10
Pomolic Acid SCHEMBL7357947 1.00 PTPN1 (1.00) PTPN1SENP1POLBPTPN2AKR1B10
Pomolic Acid SCHEMBL12181563 1.00 PTPN1 (1.00) PTPN1SENP1POLBPTPN2AKR1B10
Pomolic Acid SCHEMBL1049001 1.00 PTPN1 (1.00) PTPN1SENP1POLBPTPN2AKR1B10
Pomolic Acid SCHEMBL20971332 1.00 PTPN1 (1.00) PTPN1SENP1POLBPTPN2AKR1B10
Pomolic Acid SCHEMBL20998163 1.00 PTPN1 (1.00) PTPN1SENP1POLBPTPN2AKR1B10
Pomolic Acid SCHEMBL1049053 1.00 PTPN1 (1.00) PTPN1SENP1POLBPTPN2AKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030031734-A1 Extracts of blueberries with anti-oxidant and anti-cancer properties RUTGERS, THE STATE UNIVERSITY 2003-02-13 US disclosed
EP-0751783-B1 HYPOCHOLESTEROLEMIC, ANTIATHEROSCLEROTIC AND HYPOTRIGLYCERIDEMIC USE OF AMINOACETYLMERCAPTO DERIVATIVES MERRELL PHARMA INC (US) 2000-02-02 EP disclosed
US-5916919-A TRITERPENES DALHOUSIE UNIVERSITY (CA) 1999-06-29 US disclosed
EP-0625987-B1 AMINOACETYLMERCAPTOACETYLAMIDE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE MERRELL PHARMA INC (US) 1998-04-01 EP disclosed
WO-1993016103-A1 AMINOACETYLMERCAPTOACETYLAMIDE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE MERRELL DOW PHARMACEUTICALS INC. (US) 1993-08-19 WO disclosed