Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 1.00 |
| ▸ | SENP1 | Q9P0U3 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 0.73 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.73 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.73 |
| ▸ | PTPRF | P10586 | 3/20 | 0.73 |
| ▸ | CES1 | P23141 | 3/20 | 0.73 |
| ▸ | ACP1 | P24666 | 3/20 | 0.73 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.73 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.73 |
| ▸ | RELA | Q04206 | 3/20 | 0.73 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.73 |
| ▸ | USP7 | Q93009 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | USP2 | O75604 | 2/20 | 0.73 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.73 |
| ▸ | CTSD | P07339 | 1/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.73 |
| ▸ | CETP | P11597 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pomolic Acid SCHEMBL7357945 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBPTPN2AKR1B10 | |
| Pomolic Acid SCHEMBL7035935 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBPTPN2AKR1B10 | |
| Pomolic Acid SCHEMBL829116 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBPTPN2AKR1B10 | |
| Pomolic Acid SCHEMBL30417300 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBPTPN2AKR1B10 | |
| Epipomolic Acid SCHEMBL7035933 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBPTPN2AKR1B10 | |
| Pomolic Acid SCHEMBL7357947 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBPTPN2AKR1B10 | |
| Pomolic Acid SCHEMBL1049001 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBPTPN2AKR1B10 | |
| Pomolic Acid SCHEMBL20971332 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBPTPN2AKR1B10 | |
| Pomolic Acid SCHEMBL20998163 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBPTPN2AKR1B10 | |
| Pomolic Acid SCHEMBL1049053 | 1.00 | PTPN1 (1.00) | PTPN1SENP1POLBPTPN2AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571354-B1 | Ursolic acid for inhibiting muscle atrophy | UNIV IOWA RES FOUND (US) | 2020-07-08 | — | — | EP | disclosed |
| US-20180118657-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2018-05-03 | — | — | US | disclosed |
| US-20130203712-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2013-08-08 | — | — | US | disclosed |
| WO-2011146768-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118657-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | TNNC1, PYGM, GYS1 | PTPN1 4668/4885SENP1 264/4885POLB 3218/4885 |
| US-20130203712-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | TNNC1, PYGM, GYS1 | PTPN1 4668/4885SENP1 264/4885POLB 3218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.