Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264776 | 0.86 | TSHR (0.47) | CES2CES1TSHR | |
| SCHEMBL382321 | 0.85 | TSHR (0.50) | CES2CES1TSHR | |
| SCHEMBL129557 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CES2CES1FFAR3HDAC3 | |
| SCHEMBL133540 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CES2CES1TSHR | |
| SCHEMBL128436 | 0.79 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL127436 | 0.78 | — | — | |
| SCHEMBL10898750 | 0.77 | TSHR (0.46) | CES2CES1TSHR | |
| SCHEMBL129471 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CES2CES1FFAR3HDAC3 | |
| SCHEMBL1119103 | 0.75 | — | — | |
| SCHEMBL4623449 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1288709-A1 | A thermally bleachable dye for a color photothermographic element | EASTMAN KODAK COMPANY (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6492076-B1 | UNDERGOES CHANGE IN ELECTROMAGNETIC ABSORPTION WHEN HEATED; ANTIHALATION OR FILTER LAYERS CONTAINING ZWITTERIONIC 1-AMINOPYRIDINIUM DYE | EASTMAN KODAK COMPANY | 2002-12-10 | — | — | US | disclosed |
| US-4564619-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-01-14 | — | — | US | disclosed |