Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 3/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | FABP3 | P05413 | 1/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11742197 | 0.85 | PTGER4 (0.56) | PTGER4TSHRCLCN2CYP2C9HIF1A | |
| SCHEMBL69352 | 0.84 | TSHR (0.68) | TSHRCYP2C9HIF1AKDM4EPOLB | |
| SCHEMBL17938486 | 0.82 | TSHR (0.66) | TSHRCYP2C9HIF1AKDM4EPOLB | |
| SCHEMBL11740765 | 0.81 | TSHR (0.49) | PTGER4TSHRCLCN2CYP2C9HIF1A | |
| N-Methylanthranilic Acid SCHEMBL130356 | 0.81 | KDM4E (0.64) | CLCN2CYP2C9HIF1AKMT2AKDM4E | |
| N-Methylanthranilic Acid SCHEMBL29381752 | 0.81 | KDM4E (0.64) | CLCN2CYP2C9HIF1AKMT2AKDM4E | |
| SCHEMBL5358994 | 0.80 | SLC16A3 (0.60) | PTGER4TSHRKMT2ASLC16A3RAB9A | |
| SCHEMBL15959651 | 0.79 | TSHR (0.58) | PTGER4TSHRCLCN2CYP2C9HIF1A | |
| N-Methylanthranilic Acid SCHEMBL10796607 | 0.79 | KDM4E (0.62) | CLCN2CYP2C9HIF1AKMT2AKDM4E | |
| N-Methylanthranilic Acid SCHEMBL8552208 | 0.79 | KDM4E (0.62) | CLCN2CYP2C9HIF1AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030149038-A1 | Alpha-helix mimicry by a class of organic molecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-08-07 | — | — | US | disclosed |
| WO-2003040402-A2 | ALPHA-HELIX MIMICRY BY A CLASS OF ORGANIC MOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149038-A1 | Alpha-helix mimicry by a class of organic molecules | SERPINH1, FABP1, HSPH1 | PTGER4 4428/4885TSHR 4108/4885CLCN2 2056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.