3-Hydroxybutyric Acid, (+/-)-

3-Hydroxybutyric Acid, (+/-)-

SCHEMBL7036248

CC(O)CC(=O)O.O=C(O)C#CC(=O)O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.40
MAPT P10636 1/20 0.38
GABRR1 P24046 2/20 0.37
LMNA P02545 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
CACNA2D1 P54289 2/20 0.35
CACNB3 P54284 1/20 0.35
CACNA1C Q13936 1/20 0.35
PGR P06401 1/20 0.35
ADRA1A P35348 1/20 0.35
HTR2B P41595 1/20 0.35
CACNA2D2 Q9NY47 1/20 0.35
TP53 P04637 1/20 0.35
GPR84 Q9NQS5 4/20 0.34
FFAR1 O14842 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(R)-3-Hydroxybutanoate SCHEMBL19459353 0.89
3-Hydroxybutyric Acid, (+/-)- SCHEMBL16098949 0.89
(R)-3-Hydroxybutanoate SCHEMBL29008113 0.87
3-Hydroxybutyric Acid, (+/-)- SCHEMBL21225058 0.87 SLC22A6 (0.50) SLC22A6SMN1; SMN2MAPTGABRR1LMNA
3-Hydroxybutyric Acid, (+/-)- SCHEMBL29008114 0.87
(R)-3-Hydroxybutanoate SCHEMBL29903959 0.87
3-Hydroxybutyric Acid, (+/-)- SCHEMBL1897117 0.87 SLC22A6 (0.56) SLC22A6SMN1; SMN2MAPTGABRR1LMNA
3-Hydroxybutyric Acid, (+/-)- SCHEMBL1881926 0.87 SLC22A6 (0.56) SLC22A6SMN1; SMN2MAPTGABRR1LMNA
(R)-3-Hydroxybutanoate SCHEMBL1533862 0.87 SLC22A6 (0.56) SLC22A6SMN1; SMN2MAPTGABRR1LMNA
(R)-3-Hydroxybutanoate SCHEMBL336331 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659421-B1 2-Phenyl-3-aroylbenzothiophenes for treating menstrual symptoms LILLY CO ELI (US) 2003-03-12 EP disclosed
EP-0659421-A1 2-Phenyl-3-azoylbenzothiophenes for treating menstrual symptoms ELI LILLY AND COMPANY (US) 1995-06-28 EP disclosed