Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11024803 | 1.00 | SIRT2 (0.36) | SIRT2 | |
| SCHEMBL5940458 | 0.90 | — | — | |
| SCHEMBL1240082 | 0.82 | SIRT2 (0.37) | SIRT2 | |
| SCHEMBL1242661 | 0.82 | SIRT2 (0.37) | SIRT2 | |
| SCHEMBL1241925 | 0.82 | SIRT2 (0.37) | SIRT2 | |
| SCHEMBL9950942 | 0.82 | SIRT2 (0.37) | SIRT2 | |
| SCHEMBL1242607 | 0.80 | SIRT2 (0.35) | SIRT2 | |
| SCHEMBL23781421 | 0.76 | SIRT2 (0.33) | SIRT2 | |
| SCHEMBL1241827 | 0.75 | — | — | |
| SCHEMBL10723512 | 0.72 | SIRT2 (0.40) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065117-A1 | Modified silicone compound, process of producing the same, and cured object obtained therefrom | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-0197540-B1 | USE OF AMINES FOR STABILIZING POLYSILOXANE FLUIDS | WACKER-CHEMIE GMBH (DE) | 1991-11-13 | — | — | EP | disclosed |
| US-5015717-A | Sulfur-containing organopolysiloxane waxes and a method for preparing the same | WACKER SILICONES CORPORATION (US) | 1991-05-14 | — | — | US | disclosed |
| US-4985135-A | Surface silylated zeolite cataysts, and processes for the preparation, and use of said catalysts in the production of high octane gasoline | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| US-4906599-A | Surface silylated zeolite catalysts, and processes for the preparation, and use of said catalysts in the production of high octane gasoline | EXXON RESEARCH & ENGINEERING CO. (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0274100-A2 | Sulfur containing organopolysiloxane waxes and a method for preparing the same | Wacker Silicones Corporation (US) | 1988-07-13 | — | — | EP | disclosed |
| US-4612055-A | Stabilized blends of thiofunctional polysiloxane fluids and organopolysiloxane fluids and a process for stabilizing the same | SWS SILICONES CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |
| EP-0033517-B1 | PROCESS FOR PREPARING SULFUR CONTAINING POLYSILOXANE POLYMERS, THE PRODUCTS OBTAINED THEREBY AND THE USE OF THE PRODUCTS AS CROSS-LINKING AGENTS | SWS Silicones Corporation (US) | 1985-08-21 | — | — | EP | disclosed |
| US-4289867-A | Organofunctional polysiloxane polymers and a method for preparing the same | SWS SILICONES CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |
| EP-0033517-A1 | Process for preparing sulfur containing polysiloxane polymers, the products obtained thereby and the use of the products as cross-linking agents | SWS Silicones Corporation (US) | 1981-08-12 | — | — | EP | disclosed |
| US-4046795-A | Process for preparing thiofunctional polysiloxane polymers | SWS SILICONES CORPORATION (US) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065117-A1 | Modified silicone compound, process of producing the same, and cured object obtained therefrom | ORMDL3, SGMS1, HEATR1 | SIRT2 1506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.