Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871717 | 0.91 | TACR1 (0.46) | TACR1SCDMAPK14TACR3 | |
| SCHEMBL7039564 | 0.86 | TACR1 (0.41) | TACR1SGMS2CETP | |
| SCHEMBL7039431 | 0.85 | TACR1 (0.41) | TACR1SGMS2CETP | |
| SCHEMBL6016582 | 0.82 | TACR1 (0.44) | TACR1HTR2AKCNH2SCDMAPK13 | |
| SCHEMBL7042999 | 0.81 | TACR1 (0.62) | TACR1SGMS2 | |
| SCHEMBL6016561 | 0.77 | TACR1 (0.52) | TACR1SGMS2CETP | |
| SCHEMBL6870660 | 0.76 | TACR1 (0.52) | TACR1 | |
| SCHEMBL6871260 | 0.76 | TACR1 (0.51) | TACR1 | |
| SCHEMBL6869431 | 0.76 | TACR1 (0.52) | TACR1TACR3 | |
| SCHEMBL7045412 | 0.75 | SYK (0.43) | TACR1CCR2CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187814-B1 | 5-PHENYL-PYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2004-08-18 | — | — | EP | claimed |