Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 5/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871717 | 0.90 | TACR1 (0.46) | TACR1SCDMKNK1TACR3MAPK14 | |
| SCHEMBL6016479 | 0.86 | TACR1 (0.53) | TACR1RAF1BRAF | |
| SCHEMBL6016707 | 0.85 | TACR1 (0.50) | TACR1TACR3MAPK14 | |
| SCHEMBL6016667 | 0.85 | TACR1 (0.49) | TACR1TACR3 | |
| SCHEMBL7036633 | 0.82 | TACR1 (0.42) | TACR1SCDTACR3HTR2AHTR2C | |
| SCHEMBL6016586 | 0.80 | TACR1 (0.64) | TACR1 | |
| SCHEMBL6016604 | 0.78 | TACR1 (0.53) | TACR1TACR3 | |
| SCHEMBL6016612 | 0.77 | TACR1 (0.54) | TACR1KCNH2RAF1BRAF | |
| SCHEMBL6016461 | 0.77 | TACR1 (0.64) | TACR1RAF1BRAF | |
| SCHEMBL6016603 | 0.77 | TACR1 (0.50) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187815-B1 | 4-PHENYL-PYRIMIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2006-02-08 | — | — | EP | claimed |