Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531103 | 0.93 | NR1H4 (0.46) | ALDH1A1KDM4ELMNATSHRHSD17B10 | |
| SCHEMBL7036693 | 0.89 | HPSE (0.48) | HPSESNCAKMT2AMEN1ALDH1A1 | |
| SCHEMBL7036697 | 0.89 | HPSE (0.48) | HPSESNCAKMT2AMEN1ALDH1A1 | |
| SCHEMBL7529010 | 0.85 | KMT2A (0.60) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL7529022 | 0.85 | KMT2A (0.60) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL7646488 | 0.83 | KMT2A (0.55) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL7646483 | 0.83 | KMT2A (0.55) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL7526766 | 0.83 | KMT2A (0.55) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL7531099 | 0.80 | PTPN1 (0.46) | KMT2AMEN1ALDH1A1KDM4ELMNA | |
| SCHEMBL7646721 | 0.80 | PTPN1 (0.46) | KMT2AMEN1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | TELIK, INC. | 2002-03-14 | — | — | US | claimed |
| EP-1289936-A1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK, INC. (US) | 2003-03-12 | — | — | EP | disclosed |
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |
| WO-2001094295-A1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK, INC. (US) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | SLC2A1, SLC2A8, SLC2A2 | HPSE 377/4885SNCA 3814/4885KMT2A 3788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.